DOPAMINERGIC NEUROMODULATION OF SPIKE TIMING DEPENDENT PLASTICITY IN MATURE ADULT RODENT AND HUMAN CORTICAL NEURONS

Dopaminergic Neuromodulation of Spike Timing Dependent Plasticity in Mature Adult Rodent and Human Cortical Neurons

Synapses in the cerebral cortex constantly change and this dynamic property regulated by the action of neuromodulators such as dopamine (DA), is essential for reward learning and memory.DA modulates 510 spike-timing-dependent plasticity (STDP), a cellular model of learning and memory, in juvenile rodent cortical neurons.However, it is unknown wheth

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Automated Detection of Major Depressive Disorder With EEG Signals: A Time Series Classification Using Deep Learning

Major depressive disorder (MDD) has been considered a severe and common ailment with effects on functional frailty, while its clear manifestations are shrouded in mystery.Hence, manual detection of MDD is a challenging and subjective task.Although Electroencephalogram (EEG) signals have shown promise in aiding diagnosis, further enhancement is Hair

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ARCHAEOLOGICAL DOCUMENTATION OF A DEFUNCT IRAQI TOWN

The subject of this article is the possibilities of the documentation of a defunct town from the Pre-Islamic period to Early Islamic period.This town is located near the town Makhmur in Iraq.The Czech archaeological mission has worked at this dig site.This Cultural Heritage site is threatened by war because in the vicinity are positions of ISIS.For

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Characterization of Genome-Wide DNA Methylation and Hydroxymethylation in Mouse Arcuate Nucleus of Hypothalamus During Puberty Process

Background: Pulsatile pituitary gonadotropin secretion governed by hypothalamic gonadotropin-releasing hormone (GnRH) is essential for the pubertal onset.The epigenetic mechanism underlying the activation of GnRH-dependent regulatory axis in hypothalamus remains elusive.This study aims to explore the potential correlation between the signature of D

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